Institut für Medizinische Statistik - UMG

Markus Harden

Doktorand - AG Klinische Studien
Humboldtallee 32, Erdgeschoss 153
Kurzer Lebenslauf

[09/2014-11/2014] Praktikum bei der Novartis Pharma AG, Basel, Schweiz
[10/2013-11/2013] Praktikum bei der Novartis Pharma AG, Basel, Schweiz
[seit 04/2013] Doktorand des Promotionsstudienganges
"Humanwissenschaften in der Medizin",
Universitätsmedizin Göttingen
[seit 07/2012] Wissenschaftlicher Mitarbeiter
am Institut für Medizinische Statistik,
Universitätsmedizin Göttingen
[06/2012] Abschluss: Master of Science in Mathematik
[09-12/2011] Auslandssemester an der Université Rennes I,
[09/2009] Abschluss: Bachelor of Science in Mathematik
[2006 - 2012] Studium der Mathematik mit Nebenfach Volkswirtschaftslehre
an der Georg-August-Universität Göttingen
[1987] Geboren in Wilhelmshaven


Statistik in der Medizin
Statistische Methoden des Drug Monitoring
Hochdimensionale Daten


Back schools for low back pain;
in collaboration with Prof. Sebastian Straube (Division of Preventive Medicine, Department of Medicine, University of Alberta, Edmonton, Canada);
Funded by: the Federal Ministry of Education and Research (BMBF); Project duration: 2014-2015.

Biomarker driven individualized immunosuppression after liver transplantation;
in collaboration with Prof. Jürgen Brockmöller (PI, Dept. Clinical Pharmacology); Funded by: the Federal Ministry of Education and Research (BMBF); Project duration: 2012-2015.

Biostatistical Methods for Efficient Evaluation of Individualized Therapies (BIMIT);
in collaboration with the University Heidelberg, University Bremen and pharmaceutical industries;
PIs: Prof Meinhard Kieser (project coordinator), Institute of Medical Biometry and Informatics of the University Heidelberg; Prof Werner Brannath, Competence Center for Clinical Trials of the University Bremen and Prof Tim Friede, Department of Medical Statistics of the University Medical Center Göttingen;
Funded by: the Federal Ministry of Education and Research (BMBF); Project duration: 2013-2016.

EU-CERT-ICD - Comparative Effectiveness Research to Assess the Use of Primary Prophylactic Implantable Cardioverter Defibrillators in Europe;
Consortium of 19 European organisations; Consortium coordinator: Prof Markus Zabel from the Heart Center of the University Medical Center Göttingen
Funded by: the European Commision (EC); Project duration: 2013-2017.



[2] Masterthesis: Das Behrens-Fisher-Problem für hochdimensionale Split-Plot-Designs (2012)
[1] Bachelorthesis: Das nichtparametrische Behrens-Fisher-Problem mit Approximation nach Atiqullah (2009)


[5] 60. GMDS-Jahrestagung 2015, Krefeld: Reporting of preferred study outcomes in randomized controlled trials of back schools for chronic low back pain - systematic review and meta-analysis.
[4] Biometrisches Kolloquium 2014, Bremen: Construction of target ranges in transplantation data.
[3] ISCB 2013, München: Adaptive treatment designs for dose adjustments in immunosuppression.
[2] Doktorandentreffen Stochastik 2013, Göttingen: Adaptive Behandlungsstrategien für Therapeutisches Drug Monitoring.
[1] KSFE 2013, Ulm: Das Behrens-Fisher-Problem für hochdimensionale Split-Plot-Designs.


[1] ISCB 2014, Wien: Calculation of target range values on a continuous scale in immunosuppression following solid organ transplantation


[1] Harden M. (2013) Das Behrens-Fisher-Problem für hochdimensionale Split-Plot-Designs. [Open Access]
[2] Krasnianski, A., Bohling, G. T., Harden, M., & Zerr, I. (2015). Psychiatric symptoms in patients with sporadic Creutzfeldt-Jakob disease in Germany. The Journal of clinical psychiatry, 76(9), 1209-1215. [DOI]
[3] Straube, S., Harden, M., Schröder, H., Arendacka, B., Fan, X., Moore, R. A., & Friede, T. (2016). Back schools for the treatment of chronic low back pain: possibility of benefit but no convincing evidence after 47 years of research-systematic review and meta-analysis. Pain. [DOI]
[4] Wetz, A. J., Perl, T., Brandes, I. F., Harden, M., Bauer, M., & Bräuer, A. (2016). Unexpectedly high incidence of hypothermia before induction of anesthesia in elective surgical patients. Journal of Clinical Anesthesia, 34, 282-289. [DOI]
[5] Balcarek, Peter, et al. (2016). Results of medial patellofemoral ligament reconstruction compared with trochleoplasty plus individual extensor apparatus balancing in patellar instability caused by severe trochlear dysplasia: a systematic review and meta-analysis. Knee Surgery, Sports Traumatology, Arthroscopy, 1-9. [DOI]
[6] Schütz, E., et al. (2017). Graft-derived cell-free DNA, a noninvasive early rejection and graft damage marker in liver transplantation: A prospective, observational, multicenter cohort study. PLoS medicine, 14(4), e1002286. [DOI]