• 
  M. Sc. Studiengang "Applied Statistics"
  German English Application for winter term is possible from April 1st to 15th May of each year!
  
  

Burak Kürsad Günhan

PhD Student - WG Clinical Trials

Phone:

0551-39-19716

Telefax:

0551-39-4995

E-Mail:

Burak.Gunhan@med.uni-goettingen.de

Office room:

Humboldtallee 32, Floor 3, 3.111

ORCID iD:

 orcid.org/0000-0002-7454-8680

Publons iD:

https://publons.com/a/1474663

Github:

https://github.com/gunhanb

Website:

http://bkguenhan.netlify.com/

Research interests

• Bayesian statistics
• Hierarchical models
• Network meta-analyis
• Phase-I dose-escalation trials
• PK/PD models in drug development

Publications

• B. K. Günhan, S. Weber, T. Friede, 2020. A Bayesian time-to-event pharmacokinetic model for phase I dose-escalation trials with multiple schedules. Submitted for publication ( Preprint.).
• B. K. Günhan, S. Weber, A. Seroutou, T. Friede, 2020. Sequential phase I dose-escalation trials with multiple schedules. submitted for publication ( Preprint.).
• B. K. Günhan, C. Röver, T. Friede, 2019. Random-effects meta-analysis of few studies involving rare events. Research Synthesis Methods ( Open Access.).
• B. K. Günhan, T. Friede, L. Held, 2018. A design-by-treatment interaction model for network meta-analysis and meta-regression with integrated nested Laplace approximations. Research Synthesis Methods;9:179-194 (Open Access ).
• T. Friede, M. Posch, S. Zohar, [and 19 others including B. K. Günhan], 2018. Recent advances in methodology for clinical trials in small populations: the InSPiRe project. Orphanet Journal of Rare Diseases;13:186 (Open Access ).

Projects

• Multicenter, open-label Phase Ib dose-escalation and dose-confirmational study for the tolerability and safety of N-hydroxy-N'-phenyl-octanediamide in patients with mild Alzheimer's disease:
  
  Funded by: Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE); Project duration: Present-2016.
  
  
• Development of innovative methods for the design and analysis of clinical studies in rare diseases or small stidy populations (InSPiRE):
  
  Funded by: European Union's Seventh Framework Programme.

Teaching

• Winter Term 2019/2020, Analysis of Time-to-Event Data (MSc. in Applied Statistics).
• Winter Term 2018/2019, Analysis of Time-to-Event Data (MSc. in Applied Statistics).
• Winter Term 2019/2020, Introduction to Statistics (MSc. in Neuroscience).
• Winter Term 2018/2019, Introduction to Statistics (MSc. in Neuroscience).
• Winter Term 2017/2018, Introduction to Statistics (MSc. in Neuroscience).

Oral Presentations

• B. K. Günhan, May 2019. Model-based meta-analsi using arm-based models.
  Bayes-Pharma (Applied Bayesian Biostatistics Workshop) , Lyon, France.
  
• B. K. Günhan, March 2019. Meta-analysis of few studies involving rare events.
  DAGStat Conference 2019, Münich, Germany.
  
• B. K. Günhan, Februay 2019. Random-effects meta-analysis of few studies involving rare events.
  Symposium on meta-analysis of rare events Göttingen, Germany.
  
• B. K. Günhan, December 2018. Phase I dose-escalation trials with more than one dosing regimen.
  Worksop of the working group Bayes method of the International Biometric Society, German Region, Göttingen, Germany.
  
• B. K. Günhan, March 2018. A design-by-treatment interaction model for network meta-analysis and meta-regression with integrated nested Laplace approximations.
  64. Biometrisches Kolloquium, IBS, Frankfurt, Germany.
  
• B. K. Günhan, April 2017. A design-by-treatment interaction model for network meta-analysis with integrated nested Laplace approximations.
  Conference on Methodology for Clinical Trials in Small Populations and Rare Diseases, University of Warwick, Coventry, England (via Skype).
  
• B. K. Günhan, December 2016. Network meta-analysis using integrated nested Laplace approximations (INLA).
  Worksop of the working group Bayes method of the International Biometric Society, German Region, Mainz, Germany.
  

Poster Presentations

• B. K. Günhan, S. Weber, A. Serotou, T. Friede, July 2018. Guiding Phase-I dose-escalation trials with dosing regimen changes.
  IBC (International Biometric Conference), Barcelona, Spain.
  
• B. K. Günhan, C. Röver, T. Friede, June 2018. Meta-analysis of rare events with few studies.
  PSI annual conference (Statisticians in Pharmaceutical Industry), Amsterdam, Holland.
  
• B. K. Günhan, S. Weber, A. Serotou, T. Friede, October 2017. Guiding Phase-I dose-escalation trials with dose regimen changes.
  Novartis Biostatistics Conference, Basel, Switzerland (Best Poster Award).
  

Software packages

• B. K. Günhan, 2018. MetaStan: Bayesian Meta-Analysis via 'Stan'.
  Stable version on CRAN: https://CRAN.R-project.org/package=MetaStan.
  

• B. K. Günhan, 2017. nmaINLA: Network Meta-Analysis using Integrated Nested Laplace Approximations.
  Stable version on CRAN: https://CRAN.R-project.org/package=nmaINLA.
  

Master Thesis

• B. K. Günhan, Supervised by Prof. Leonhard Held and Dr. Rafael Sauter, February 2016. Network meta-analysis with integrated nested Laplace approximations. University of Zurich, Zurich, Switzerland (Open Access).