Institut für Medizinische Statistik - UMG

David Ellenberger

Doktorand - AG Klinische Studien
Humboldtallee 32, Erdgeschoss 155

Nichtparametrische Statistik,
Statistik in der Medizin,
Hochdimensionale Testverfahren,
Observational Studies,
Changepoint Analysen
Kurzer Lebenslauf

[seit 01/2012] Wissenschaftlicher Mitarbeiter,
Abteilung Medizinische Statistik,
Georg-August-Universität Göttingen
[12/2011] Abschluss zum Diplom Mathematiker,
Georg-August-Universität Göttingen
[2005 - 2011] Studium der Mathematik an der
Georg-August-Universität Göttingen und
der University of Warwick in Coventry
[1986] Geboren in Kassel


60. GMDS-Jahrestagung 2015, Krefeld: Exact methods for Changepoint detection for binary endpoints with applications to clinical registries.

59. GMDS-Jahrestagung 2014, Göttingen: Comparison of methods for adjustment of calendar time effects when analyzing register data.

60. Biometrisches Kolloquium 2014, Bremen: Use of simulation methods in the assessment of competing analysis strategies for disease registries accounting for calendar time effects.

Kolloquium "Statistische Methoden in der empirischen Forschung" WS 2012/2013, Berlin: Potential pitfalls and points to consider when analyzing high-dimensional repeated measurements.

58. Biometrisches Kolloquium 2012, Berlin: High- and Low- Dimensional Repeated Measures: Improved Approximations.


DAGStat 2016, Göttingen: Exact methods for change point detection in binary sequences.

ECTRIMS 2015, Barcelona: Validation of the German version of the Multiple Sclerosis Work Difficulties Questionnaire (MSWDQ).

34. Annual Conference of the International Society for Clinical Biostatistics (ISCB) 2013, München: Simulation methods for design and analysis of disease registries.


Stork L, Ellenberger D, Beissbarth T, Friede T, Lucchinetti C, Colleen A, Brück W, Metz I (2017). Apheresis therapy in immunopathologically classified multiple sclerosis patients. JAMA Neurology (2017) (in press).

Huppke P, Huppke B, Ellenberger D, Rostasy K, Hummel H, Stark W, Brück W, Gärtner J. (2017). Huppke, Peter, et al. "Therapy of highly active pediatric multiple sclerosis. Multiple Sclerosis Journal (2017): 1352458517732843 [Full text]

Bramlage CP, Wallbach M, Ellenberger D, Deutsch C, Minguet J, Smith KH, Stock J, Goninski A, Bramlage P, Koziolek M, Mueller GA (2017). Variables to Predict Nephrological Disease in General, and Glomerulonephritis in Particular, in Patients with Microhematuria. Journal of Clinical Medicine Research 9(7) 2017: 560. [Full text]

Ellenberger D , Friede (2016). An unconditional test for change point detection in binary sequences with applications to clinical registries. Methods of Information in Medicine 55: 367–372. [Full text]

Metz I, Beißbarth T, Ellenberger D, Pache F, Stork L, Ringelstein M, Aktas O, Jarius S, Wildemann B, Dihazi H, Friede T, Brück W, Ruprecht K and Paul F. (2016). Serum peptide reactivities may distinguish neuromyelitis optica subgroups and multiple sclerosis. Neurol Neuroimmunol Neuroinflamm. April 2016 vol. 3 no. 2 e204 [Full text]

Sterz C, Ellenberger D, Meißner H, Friede T, Flachenecker P. (2016). Employment-associated factors in multiple sclerosis: Results of a cross-sectional study in Germany. Edorium J Disabil Rehabil 2016; 2:24–33 [Full text]

Fischer TH, Herting J, Eiringhaus J, Pabel S, Hartmann NH, Ellenberger D, Friedrich M, Renner A, Gummert J, Maier LS, Zabel M, Hasenfuss G, Sossalla S. (2015). Sex-dependent alterations of Ca 2+ cycling in human cardiac hypertrophy and heart failure. Europace 2015 Oct 22. pii: euv313 [Preprint]

Rommer PS, Buckow K, Ellenberger D, Friede T, Pitschnau-Michel D, Fuge J, Stüve O, Zettl UK for the German Multiple Sclerosis (MS) Registry of the German National MS Society (DMSG) (2015). Patients’ characteristics influencing the longitudinal utilization of steroids in multiple sclerosis – an observational study. European Journal of Clinical Investigation 45: 587-593 [Abstract]

Knösel M, Ellenberger D, Göldner Y, Sandoval P, Wiechmann D. (2015). In-vivo durability of a fluoride-releasing sealant (OpalSeal) for protection against white-spot lesion formation in orthodontic patients. Head & Face Medicine 2015; 11: 11 [Full text]

Pauly M, Ellenberger D, Brunner E. (2015). Analysis of high-dimensional one group repeated measures designs. Statistics 2015; 49(6): 1243–1261 [Full text]

Ströbel P, Zettl A, Shilo K, Chuang WY, Nicholson AG, Matsuno Y, Gal A, Laeng RH, Engel P, Capella C, Marino M, Chan JK, Rosenwald A, Travis W, Franks TJ, Ellenberger D, Schaefer IM, Marx A. (2014). Tumor genetics and survival of thymic neuroendocrine neoplasms: A multi-institutional clinicopathologic study. Genes Chromosomes Cancer 2014 Apr; 53:738-749. [Abstract]

Huppke P, Hummel H, Ellenberger D, Pfeifenbring S, Stark W, Huppke B, Brück W, Gärtner J. (2014) JC virus antibody status in a pediatric multiple sclerosis cohort: prevalence, conversion rate and influence on disease severity. Mult Scler. (ePub - ahead of print). [Abstract]

Flachenecker P, Buckow K, Pugliatti M, Kes VB, Battaglia MA, Boyko A, Confavreux C, Ellenberger D, Eskic D, Ford D, Friede T, Fuge J, Glaser A, Hillert J, Holloway E, Ioannidou E, Kappos, Kasilingam E, Koch-Henriksen N, Kuhle J, Lepore V, Middleton R, Myhr KM, Orologas A, Otero S, Pitschnau-Michel D, Rienhoff O, Sastre-Garriga J, Schyns-Liharska T, Sutovic D, Thalheim C, Trojano M, Vlasov YV, Yaldizli Ö, for the EUReMS Consortium. (2014) Multiple sclerosis registries in Europe - results of a systematic survey. Mult Scler. 2014 Oct;20(11):1523-32. [Abstract]

Engelke W, Glombek J, Psychogios M, Schneider S, Ellenberger D, Santander P. (2014) Displacement of oropharyngeal structures during suction-swallowing cycles. European Archives of Oto-Rhino-Laryngology July 2014; 271(7):1987-1997. [Abstract]

Huppke B, Ellenberger D, Rosewich H, Friede T, Gärtner J, Huppke P. (2014) Clinical presentation of pediatric multiple sclerosis before puberty. Eur J Neurol 2014 Mar; 21(3): 441-6. [Abstract]

Heeg M, Mertens A, Ellenberger D, Müller GA, Patschan D. (2013) Prognosis of AKI in malignant diseases with and without sepsis. BMC Anesthesiology 2013; 13:36. [Abstract]

Fischer T, Herting J, Tirilomis T, Renner A, Neef S, Toischer K, Ellenberger D, Förster A, Schmitto J, Gummert J, Schöndube F, Hasenfuss G, Maier L, Sossalla S. (2013) Ca2+/Calmodulin-Dependent Protein Kinase II and Protein Kinase A Differentially Regulate Sarcoplasmic Reticulum Ca 2+ Leak in Human Cardiac Pathology. CIRCULATION 2013; 128(9): 970–981. [Abstract]

Koziolek MJ, Mühlhausen J, Friede T, Ellenberger D, Sigler M, Huppke B, Gärtner J, Müller GA, Huppke P. (2013) Therapeutic apheresis in pediatric patients with acute CNS inflammatory demyelinating disease. Blood Purification 2013; 36:92–97. [Abstract]

Pugliatti M, Eskic D, Mikolcić T, Pitschnau-Michel D, Myhr K-M, Sastre-Garriga J, Otero S, Wieczynska L, Torje C, Holloway E, Rienhoff O, Friede T, Buckow K, Ellenberger D, Hillert J, Glaser A, Flachenecker P, Fuge J, Schyns-Liharska T, Kasilingam E, Moretti A, Thalheim C for the EUReMS Consortium. (2012) Assess, compare and enhance the status of Persons with Multiple Sclerosis (MS) in Europe: a European Register for MS. Acta Neurologica Scandinavica 2012; 126 (Suppl. 195): 24–30. [Abstract]

Diplomarbeit (Georg-August-Universität, 2011): Verbesserung des Chen-Qin-Test im Ein-Gruppen-Design. [Full text]